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KMID : 1189120090060020121
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대한의학유전학회지
2009 Volume.6 No. 2 p.121 ~ p.130
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Genetic Polymorphisms in Patients with Endometriosis in the Korean Population
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Lee Gyoung-Hun
Choi Young-Min
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Abstract
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To analyze a wide variety of polymorphisms in patients with endometriosis is important since this disease has a strong genetic component. Until now, more than 30 Korean studies have been performed in order to elucidate the possible role of specific polymorphisms in the susceptibility to endometriosis. The most meaningful polymorphisms in Korean patients with endometriosis came from studies investigating GSTM1, AhRR, ER-alpha, VEGF, AHSG, and TNF-alpha. However, following studies should be made to confirm the consistency of the data to have some implications in the prediction of endometriosis. In this review, we also present the future direction of the association studies in complex trait disease such as endometriosis.
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KEYWORD
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Endometriosis, Genetic polymorphism
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